Replicated associations were observed for 4 of the 10 genes (Table 4): CNGB3 (macular degeneration in EAs, OR = 1.2 [1.0–1.4], p = 0.03), F5 (stroke in AAs, OR = 1.4 [1.0–1.9], p = 0.04), GPR98 (convulsions in AAs, OR = 1.9 [1.1–3.3], p = 0.02) and HGFAC (GI bleeding in EAs, OR = 1.2 [1.0–1.4], p = 0.02). The gene discussed is ADGRV1; the disease is convulsion.