SOD1 and amyotrophic lateral sclerosis: Atypical clinical features can be associated, defining “ALS plus” [1] syndromes with signs and symptoms involving the sensory (particularly in SOD1-linked FALS) [13–22], extrapyramidal [14, 23–31], cerebellar [23, 32], ocular [33, 34], and autonomic [35] systems.