Cytotoxin-associated gene A (CagA) is a cytotoxin-associated protein, linked with peptic ulcer and gastric cancer [6]. H. pylori strains can be grouped as Western and East-Asian subtypes based on polymorphism in 3′ repeat region of the cagA gene, which results in the variation of clinical outcome in East-Asian and Western countries. This evidence concerns the gene S100A8 and Peptic ulcer.