It was reported that sCD14 is elevated in inflammatory diseases and that it is a valuable marker in monitoring the response of patients to treatment.23 It was also shown to increase in type 2 diabetes mellitus patients, with the elevation attributed to damaged endothelial cells.24 A recent investigation demonstrated that CD14 modulates adipose tissue inflammatory activity and insulin resistance.25 Most of our patients had localized infections, which would not result in a systematic response. This evidence concerns the gene CD14 and Insulin resistance.