CRP and atherosclerosis: In this paper, we review two recognition functions of pentameric CRP which are relevant to cardiovascular disease: the phosphocholine- (PCh-) binding function of native pentameric CRP that has been implicated in acute myocardial infarction and ischemia/reperfusion (I/R) injury and the atherogenic low-density lipoprotein- (LDL-) binding function of nonnative pentameric CRP that has been implicated in atherosclerosis.