PAF1 and pachyonychia congenita: Similar change in PD2/Paf1 expression was also observed in the KPC (KrasG12D/p53/Pdx1-Cre) mouse model of PC, where there was increased PD2/Paf1 mRNA level in 25-week old KPC mice, having advanced pancreatic ductal adenocarcinoma (Figure S1A).