Similarly, patients with higher PTOV1 expression level had significantly shorter survival time in groups of: pT1-2 (P < 0.001) (Figure 4D), lymph node metastasis positive (including: pN1, pN2 and pN3) (P < 0.001) (Figure 4E) and pM0 (P < 0.001) (Figure 4F). The gene discussed is PTOV1; the disease is metastatic malignant neoplasm in the lymph nodes.