BMP2 and neoplasm: In addition, there were higher BMP-2 mRNA levels in NSCLC samples with lymph node metastasis (28 samples, 0.8994 ± 0.15196) compared to NSCLC samples without lymph node metastasis (33 samples, 0.8164 ± 0.13218) (P = 0.026), as well as in tumor stage T3–4 samples (12 samples, 0.9632 ± 0.1066) compared to tumor stage T1 samples (18 samples, 0.8260 ± 0.13904) or T2 samples (31 samples, 0.8290 ± 0.14797) (P = 0.014) (Table 1).