In addition, estrogen treatment attenuated the liver dysfunction and intestine injury caused by sepsis in rats with decreased serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels and ameliorated oxidative organ damage [13], while testosterone receptor blockade with flutamide following trauma-hemorrhage restored immune depression and significantly decreased the mortality after a subsequent septic challenge in male animals [14]. Here, GPT is linked to Sepsis.