Related to testes-specific, vespid and pathogenesis protein-1 (RTVP-1), or glioma pathogenesis-related protein 1, is highly expressed in GBM and glioma cell lines, but not in normal adult brain, nor in low grade astrocytomas, oligodendrogliomas or other nervous system tumors (6–9). This evidence concerns the gene GLIPR1 and central nervous system cancer.