Certain studies have demonstrated that FDG indirectly reflects the hypoxic status of malignant tumors (9,10,15–18) since FDG is associated with hypoxia markers, including Glut-1, phosphoinositide 3-kinase (PI3K) and hypoxia inducible factor-1α (HIF-1α) (2,9,10,15–17). Here, SLC2A1 is linked to cancer.