NFE2L2 and hypertensive disorder: For example, diets containing specific Nrf2 activators that act on Keap1 thiols as well as activators that act on the phosphorylation states of Nrf2 allowing more efficient Nrf2 translocation to the nucleus - the end result is a more normal redox status of cells with consequences that include decreased probabilities of developing hypertension and developing atherosclerotic lesions.