CXCL8 and acute promyelocytic leukemia: One study using HL60 human promyelocytic leukaemia cells reported a secretory pathway for IL-8 that involved an autophagy-related structure termed the TOR-autophagy spatial coupling compartment (TASCC).36 It is unclear if the TASCC structure is present in the MDM used in our study or if this is the only secretory pathway used by IL-8.