Among the statistically significant ones, colorectal cancer (KEGG pathway hsa05210) was present due to the predicted interactions between these miRNAs and the following target genes: TCF4, APC, SMAD4, MAPK8, PIK3CG, PIK3CD, DCC, PIK3CG, PIK3CA and MAPK1. This evidence concerns the gene SMAD4 and colorectal cancer.