DUX4 and facioscapulohumeral muscular dystrophy: Indeed, when expression array data are analyzed based on a priori knowledge of genes induced by DUX4-transduction in skeletal muscle cells, there is a significant elevation of these genes in FSHD muscle ([83] and SJT unpublished data); and a focused analysis shows that DUX4 and DUX4 target genes are expressed in fetal FSHD muscles [84].