The positive rate of serum anti-Sm in the LN patients was significantly higher in the renal EBV-expressing group than in the non-expressing group (P<0.05), while the positive rates of serum ANA, anti-RNP, anti-SSA, anti-SSB, anti-Jo-1 and anti-ds-DNA were not found to be significantly different between the two groups (P>0.05) (Table IV). The gene discussed is SSB; the disease is lobular neoplasia.