In conclusion, BRCAA1 monoclonal antibody- and Her2 antibody-conjugated amphiphilic polymer-modified core-shell CdSe/ZnS quantum dots were successfully prepared, exhibited good biocompatibility and strong stable fluorescence signals, and were successfully used for in vitro and in vivo targeted imaging of gastric cancer MGC803 cells. The gene discussed is ARID4B; the disease is gastric cancer.