Regarding cholangiocarcinoma (CCA), a study reported that LCN2 expression was detected in the CCA cell line, HuCCA-1, but not in 4 hepatocellular carcinoma cell lines, HepG2, HCC-S102, SK-Hep-1, and Alexander, suggesting the expression might be specific to CCA [43]. The gene discussed is LCN2; the disease is cholangiocarcinoma.