Compared with tumor-free tissues, immunostaining intensity analysis of cancer breast biopsies, quantified according to a modified Allred scoring, revealed a significant decrease in CD74 expression in the neoplastic glandular compartment (Mann-Whitney test, p=0.019; Fig. 4D), contrasting with an increased expression in the peritumoral stroma (Mann-Whitney test, p<0.001; Fig. 4D). The gene discussed is CD74; the disease is cancer.