Among them, C-X-C motif chemokine 10 (CXCL10; also known as interferon-γ inducible protein-10, IP-10) is a chemokine that potentially plays a role in the immunopathogenesis of autoimmune disease such as rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, and idiopathic inflammatory myopathy (IIM) [3-6]. The gene discussed is CXCL10; the disease is systemic sclerosis.