SW480/WWOX demonstrated decreased adhesion to fibronectin, consistent with previous findings for ovarian cancer cell lines PEO1, SCOV3 [35] and laminin, which has been identified as a predictive factor for tumour progression [54], whereas HT29/WWOX demonstrated increased adhesion to fibronectin and collagen I. These differences imply that diverse adhesion may reflect the process of cell remodelling of HT29. Here, FN1 is linked to ovarian cancer.