SW480/WWOX demonstrated decreased adhesion to fibronectin, consistent with previous findings for ovarian cancer cell lines PEO1, SCOV3 [35] and laminin, which has been identified as a predictive factor for tumour progression [54], whereas HT29/WWOX demonstrated increased adhesion to fibronectin and collagen I. These differences imply that diverse adhesion may reflect the process of cell remodelling of HT29. The gene discussed is FN1; the disease is ovarian carcinoma.