ESR1 and neoplasm: The statistical results did not show evidence of publication bias: tumor size: Begg’s test, P = 0.755, Egger’s test, P = 0.721; LNM: Begg’s test, P = 0.640, Egger’s test, P = 0.342; histological grade: Begg’s test, P = 0.583, Egger’s test, P = 0.766; expression of ER: Begg’s test, P = 0.511, Egger’s test, P = 0.360; expression of PR: Begg’s test, P = 0.537, Egger’s test, P = 0.278; expression of HER2: Begg’s test, P = 0.855, Egger’s test, P = 0.749.