(2) At the cytogenetic level, Caramazza et al. [38] showed a likely association between IDH1/2 mutations and trisomy 8 in MDS, and our results demonstrated 75% (3/4) of IDH1/2 mutants with abnormal karyotypes carried a −7/7q- karyotype. The gene discussed is IDH1; the disease is myelodysplastic syndrome.