IDH1/2 mutants carried significantly more bone marrow (BM) blasts than MDS patients with wild-type IDH1/2 (P = 0.022); no significant differences were observed in age, sex, white blood cell (WBC) count, hemoglobin, platelet count, WHO subtype, cytogenetics or IPSS. This evidence concerns the gene IDH1 and myelodysplastic syndrome.