For the cytoplasmic staining (Figure 3B, 3D, 3F, 3H, 3J, and 3L; Table 5; Figures S9–S14), significant differences were identified for Cdk4, phospho-Rb, and Cdk1 between CP-AD and N groups (with higher levels in CP-AD). The gene discussed is RB1; the disease is Alzheimer disease.