DST and neoplasm: Table 1 shows that no significant differences were found for the four parameters in plasma after FUS-induced BBB disruption as compared to the parameters for the BPA-alone group. Table 2 indicates that the maximum tumor ECF concentration (Ctmax), MRT, and area under the concentration versus time curve (AUC) values clearly increased after FUS exposure as compared with those values for the BPA administration only group.