The results showed that the expression of C10orf10 in most cases (17/20) of BC tissues was downregulated compared to the mean expression in 10 normal breast tissues (Figure 1A, 1B), and the mean expression level of C10orf10 in BC tissues (1.0±0.13) was remarkably lower than that in normal breast tissues (2.73±0.28; P = 0.0063) (Figure 1B). Here, DEPP1 is linked to breast cancer.