When we compared the data for IPAH in this paper against our results, we found a higher mutational rate for BMPR2 and ACVRL1 genes (59% vs 16.6%), finding only one mutation (p.(S160P)fs*5) in ACVRL1 in one APAH patient. This evidence concerns the gene BMPR2 and idiopathic pulmonary arterial hypertension.