PTEN and neoplasm: The slowly developing tumours (Type I) include low grade serous, endometrioid, mucinous, and a subset of clear cell carcinomas[5-7] and are characterised by genetic alterations in KRAS, BRAF, CTNNB1, PTEN, ARID1A, FBXW74, PIK3CA, PPP2R1A, and TGFBR2[7-12].