Similarly, decreased levels of β-amyloid and significantly increased levels of tau have been detected in the vitreous fluid from patients with glaucoma or diabetic retinopathy in comparison with the levels in a control group (Calabrese et al., 2010b; Pennisi et al., 2011; Siciliano et al., 2011; Cornelius et al., 2013). This evidence concerns the gene MAPT and glaucoma.