The qRT-PCR result showed that in 14 of the 16 sample pairs, fold changes (the 2-△△Ct values) were less than 1 between PCa and adjacent normal prostate tissue (Figure 1A), which indicated the PinX1 mRNA expression was down-regulated in PCa tissues compared to the adjacent normal prostate tissues. The gene discussed is PINX1; the disease is posterior cortical atrophy.