Ströbel et al., for example, suggest that in cases with advanced thymic carcinoma treatment with the multi-kinase inhibitor Sunitinib, that targets VEGFR1–3, PDGFR-α, c-KIT, FLT3, colony stimulating factor-1 (CSF1) and the RET receptor, is more effective than therapeutic regimes using single-target molecular therapies like Gefitinib, even though there are no activating mutations in the EGFR, KIT and PDGFR-α gene [35]. This evidence concerns the gene FLT1 and thymic carcinoma.