KDR and diabetes mellitus: Circulating CD45dimCD34+KDR+ EPCs decreased as a continuum from NGM to DM, as there was a reduction of approximately 40% in patients with pre-diabetes as compared with NGM patients (p = 0.018) and there was an additional reduction of these EPCs of about 40% (p = 0.042) when diabetics were compared with patients with pre-diabetes (Table 4).