Insulin-treated DM (ITDM) patients and diabetics not previously treated with antidiabetic drugs presented a worse glycemic control as compared with patients on oral hypoglycemic drugs (Figure 4).Numbers of CD45dimCD34+KDR+ EPCs were significantly reduced in diabetic patients previously treated with oral antidiabetic drugs and in diabetics not taking any hypoglycemic drug when compared with nondiabetic patients (Figure 5, A). Here, KDR is linked to diabetes mellitus.