Univariate analyses using Kaplan-Meier curves and log-rank tests indicated that BRCA1 rs1799966 (TC+CC vs. TT genotypes), radiation therapy (ever vs. never), and smoking status (never vs. ever) were significantly associated with an increased OS of advanced NSCLC patients with log-rank values of p = 0.042, 0.049, and 0.042, respectively (Fig. 1). The gene discussed is BRCA1; the disease is non-small cell lung carcinoma.