Hence, the decreased levels of leptin, resistin, and TNF-α and elevated adiponectin concentration found in instant rice-fed mice, particularly the HF-GB mice, relative to the HF group indicate that the production and release of these adipokines may have been influenced by the reduced amount of body fat, resulting in the decreased concentrations of plasma triglyceride and total cholesterol in these animal groups. The gene discussed is ADIPOQ; the disease is hydrops fetalis.