In view of all this information, it is recommended that treatment should be started after adenotonsillar surgery in children who have obstructive apnea before treatment; that steroid replacement therapy should be given in stress doses for infections that develop during treatment; that GH therapy should be stopped until the infection has subsided; and that GH therapy should be discontinued in the event of a new upper respiratory obstruction and/or sleep apnea which has developed after the onset of treatment for the first time (4,9). This evidence concerns the gene GH1 and sleep apnea syndrome.