Normal serum alanine aminotransferase (ALT = 34.8 IU/l ± 13.8 SD) levels in patients with HBsAg in our result may indicate the inactive HBsAg carrier state (After spontaneous HBeAg seroconversion, 67% to 80% of carriers have low or undetectable HBV DNA and normal ALT levels with minimal or no necroinflammation on liver biopsy) [2, 19] or may reflect mild chronic hepatitis B or hepatitis B with fluctuating disease activity [20]. This evidence concerns the gene GPT and chronic hepatitis B virus infection.