EPHA4 and familial pancreatic carcinoma: Next, a wound healing assay was performed in Panc-1 and BxPC-3 cells and the results showed that the motility of EPHA4 siRNA-transfected cells was significantly reduced compared with the control siRNA cells, which indicated that EPHA4 enhances the motility of pancreatic cancer cells (Fig. 2B and C).