Positive correlations between E-cadherin and β-catenin were also revealed in the male and female patients (P<0.0001, r=0.447; and P=0.005, r=0.326, respectively), in the younger and older individuals (P=0.002, r=0.435; and P<0.0001, r=0.406, respectively) and in the subgroups with a rectal or colonic tumor location (P=0.003, r=0.345; and P<0.0001, r=0.434, respectively) (Table IV). The gene discussed is CDH1; the disease is colonic neoplasm.