SP1 and Huntington disease: MiR-940, one of the 11 HD-associated miRNAs in the transgenic monkeys, is also predicted to target HTT. Correspondingly, although we examined miR-128a regulation of the SP1 transcription factor, other miRNAS identified in this study also bioinformatically bind to SP1 (such as miR-320, miR-133, and miR-181).