Staining with AT8, which recognizes phosphorylated tau commonly found in NFTs, and T22 did not exhibit reactivity with control brain sections (Figure 3a-c), but showed increased levels of tau oligomers in PSP brain, as well as NFTs and pre-NFTs positive for AT8 (Figure 3d-i). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.