The resulting phenotypes of Wee1 siRNA resulted in dramatic inhibition of cellular proliferation as measured by MTS reagent in H1299 non-small cell lung (NSCLC) and Daoy glioma cell lines but did not affect growth of A549 NSCLC, D54MG glioma or A2780 ovarian tumor lines (Figure 1). This evidence concerns the gene WEE1 and central nervous system cancer.