More importantly, the statistical significance of expression between grade 2 and grade 4 gliomas was 0.038 (P < 0.05) (Table 1), and the expression of the p42.3 gene was significantly different between low-grade (grade 2) gliomas and high-grade (grades 3 and 4) gliomas (P < 0.01), but there was no statistically significant difference associated with age or sex (Table 3). The gene discussed is SAPCD2; the disease is central nervous system cancer.