These findings are partly consistent to other clinical studies using different cancers, for example, Tsuji et al. reported high HO-1 expression in oral squamous cell carcinomas without lymph node metastasis, and no significant correlations between HO-1 expression and tumor sizes as well as staging[21], similar findings were also reported for gastric cancers[43]. The gene discussed is HMOX1; the disease is neoplasm.