Moreover, sequencing of the poly(T)11 allele of MRE11 in genomic DNA from EC tumours (n = 26; Table 2) showed that mutations were more frequent in tumours with loss of MRE11 than in those expressing MRE11, but the mutation status was not highly predictive for the protein status of MRE11. The gene discussed is MRE11; the disease is neoplasm.