Using the same samples, we then calculated Pearson's correlation coefficients to compare miR-34a expression levels and snoRNA U44 and U47 levels to determine if the relationship demonstrated in non-microdissected samples between GAS5-derived snoRNA levels and p53 (miR-34a being used here as a surrogate marker for p53) was also seen in microdissected colorectal tumours. The gene discussed is TP53; the disease is colorectal neoplasm.