Thus, the hazard ratio was adjusted for prior MI, aortic clamp time, number of grafts and pre-CABG medications, in addition to a variety of other confounding factors that may have affected the incidence of postoperative MI and/or serum ACE2 levels, including age, gender, BMI, hypertension, current smoking status, hyperlipidemia, diabetes mellitus and Gensini score. The gene discussed is ACE2; the disease is Hypertension.