NPPB and acute coronary syndrome: A number of previous studies have demonstrated that the levels of BNP and NT-proBNP are powerful prognostic markers across a spectrum of acute coronary syndromes (15), from unstable angina and non-ST elevation myocardial infarction to ST elevation myocardial infarction (16–18), as well as in patients with stable angina pectoris (19,20) and even in the absence of significant necrosis (21).