MAOB and multiple system atrophy: A randomized, placebo-controlled clinical trial to assess the effects of treatment with the monoamine oxidase-B inhibitor rasagiline (1 mg/day) for 48 weeks in 174 patients with possible or probable MSA-Parkinsonism type, in 39 sites in 12 countries, found no significant difference in progression in the total UMSARS score between the verum and placebo groups (45).