Among the ones not previously reported were GBP6, GPR176, SERPINB1, SERPINB3, STAT4, and CLEC2. Some of the 143 annotated transcripts suppressed in differentiating keratinocytes are known to be affected by retinoids, e.g., KRT1, KRT2, FLG and TGM1. The effect on the expression of ARCI-causing genes is given in Table 2. This evidence concerns the gene GPR176 and autosomal recessive congenital ichthyosis.