TNFRSF1B and obesity due to melanocortin 4 receptor deficiency: We explored the relationship between age, eGFR, sex, obesity, LVH, hypertension, diabetes, smoking status, peripheral vascular disease or history of atrial fibrillation with TNFα, TNFR1, TNFR2 and IL-6 in the combined HF group (Table 3).